ESPE Abstracts

Objective and hypotheses: The work was initiated to comparatively assess degree of compensation and prevalence of complications of type 1 DM in children in Uzbekistan from 1998 to 2012 according to the screening data.Method: 950 children (coverage of 80.3%) with type 1 DM were screened in 2012 within the WDF grant ‘Children’s Diabetes in Uzbekistan’, the degree of compensation and prevalence of type 1 DM chronic complications were compared...

Aim: To study incidence and risk factors of diabetic nephropathy (DN) in children and adolescents as per the Republic of Uzbekistan National Register.Method: An information list (card) and appropriate software were developed on the basis of the DN register. The cards were collected in every region of Uzbekistan to be introduced into a computer database.Results: DN screening performed in children by Alikhanova N M in 1998 showed tha...

Goal of Research: to assess the significance of the early marker of nephrine diabetic nephropathy of the Uzbek patients with the First Type of diabetes mellitus.Materials and Methods: 100 patients with DM 1 were examined, including 80 patients with normoalbuminuria (NAU) and 20 patients at the microalbuminuria (MAU). The patients were from 1 to 14 years old with the disease duration from 1 to 5 years. They included 48 bo...

Aim: The work was initiated to assess functional condition of the kidneys and to study interrelation between ACE gene I/D polymorphism and stage of chronic kidney disease in children and adolescents with type 1 diabetes mellitus (DM) in compliance with K/DOQI recommendations (2002).Materials and methods: We examined 120 children and adolescents with type 1 DM, 53 (44.2%) males and 67 (55.8%) females among them (mean age 13.8±0.24 years; 95% CI: 13.3...

Annotation: Pandemics of coronoviral infection continues affecting the wold community, and with the comprehension of its pathological physiology an interest in endocrine effects ofSARS-CoV-2 grows too. It was determined, that the main target organs affected by SARS-CoV-2 were lungs and immune system, while it is still not clear if SARS-CoV-2 has any impact on the thyroid function. In patients infected with SARS-CoV, coronovirus relevant to SARS-CoV-2, damage o...

Background: Devices for continuous subcutaneous insulin infusion have become fundamentally new and progressive step in the treatment of diabetes.Aims and objectives: To evaluate the effectiveness of insulin pump therapy in comparison with the regime of multiple daily injections (MDI) of insulin.Materials and Methods: Forty children and adolescents with type 1 diabetes from 5 to 17 ...

Objective and hypotheses: The work was initiated to assess efficacy of training and achievement of therapy targets in children and adolescents with type 1 diabetes mellitus in “Diabetes Schools”.Method: The five-day training course was conducted in “Type 1 Diabetes School” at the Center for the Scientific and Clinical Study of Endocrinology, Uzbekistan Public Health Ministry (Tashkent). The training was conducted by means of a structu...

The study was aimed at assessing the relationship between increased titers of intercellular adhesion molecules ICAM VCAM in order to assess the risk of developing vascular lesions in children with type 1 diabetesIntroduction: COVID-19 induces a systemic inflammatory response, including dysregulation and misexpression of many inflammatory cytokines [1]. Inflammatory cell recruitment and activation depends on the expression of many classes...

Objective of The Study: To study the characteristics of carbohydrate and lipid metabolism in obese children and adolescents depending on the age.Materials and Methods: We examined 171 children and adolescents aged from 6 to 16. Among them, there were 100 children and adolescents with ECO and 71 healthy children and adolescents. ECO patients were divided into 2 groups: group 1 including children with ECO aged 6-<10 yea...

Objective of the study: Comparative assessment of the achievement of target levels of the therapy for type 1 diabetes mellitus using various types of insulin in an outpatient setting.Materials and methods: The study included 100 children and adolescents with type 1 diabetes aged 4–17 years old who received basic insulin Glargin and Insulatard, and short-acting Glilusin and Actrapid. Of these, 50 children and adoles...